Cajun Chicken Pasta

Jump To Recipe
AlfredoChickenDinnerEasyEatsItalianMain CoursePastasavory

Cajun Chicken Pasta is a terrific family meal. Cajun-chicken, tomatoes and Parmesan Cheese are topped over a bed of creamy penne pasta.

Cajun-chicken, tomatoes and Parmesan Cheese topped over a bed of creamy penne pasta. Life-in-the-Lofthouse.comPasta dishes are the ultimate comfort food to me. I totally love them. My waistline doesn’t but it’s okay. 😉 What I love about this CAJUN CHICKEN PASTA is how easy and delicious it is. The homemade Alfredo sauce is a cinch to make, and the whole thing comes together in just about 30 minutes. A perfect dinner to make on those busy weeknights.

The amount of cajun seasoning was a success with my family. My kids ate it just fine. The addition of Alfredo sauce really helps neutralize the heat (and tastes amazing).

If you’re worried about the heat at all you can always cut back on it a little. But no matter what, I promise you’re going to love this awesome dish! Be sure to make some garlic bread to go with it, so you can dunk it in that heavenly sauce. 😀

Cajun-chicken, tomatoes and Parmesan Cheese topped over a bed of creamy penne pasta.



Creamy Pasta Primavera

Chicken Alfredo Pasta Bake

Chicken Ranch Pasta Bake

Chicken Mozzarella Pasta with Sun-Dried Tomatoes


Cajun Chicken Pasta

Prep Time 10 minutes
Cook Time 20 minutes
Total Time 30 minutes
Servings 2 to 4
Author Holly


  • 2 boneless, skinless chicken breasts
  • 2 tablespoons olive oil divided
  • 1 tablespoon cajun seasoning
  • 8 ounces dried penne pasta
  • 2 tablespoons unsalted butter
  • 3 cloves garlic minced
  • 1 cup heavy cream
  • 1/4 cup freshly grated Parmesan
  • Kosher salt and freshly ground black pepper to taste
  • 2 Roma tomatoes diced
  • chopped fresh parsley leaves if desired


  • In a large Ziploc bag, add chicken, 1 tablespoon olive oil and cajun seasoning. Rub and shake to coat chicken.
  • Heat remaining 1 tablespoon olive oil in a large skillet over medium high heat. Add chicken and cook about 6 minutes on each side. Remove to a plate and cover with foil keep warm.
  • In a large pot of boiling salted water, cook penne pasta according to package instructions; drain well.
  • Wipe skillet clean (be careful it will be hot!) and melt butter over medium heat. Add garlic, and cook, stirring frequently, until fragrant.
  • Gradually whisk in heavy cream. Cook, whisking constantly, until incorporated, about 1-2 minutes. Stir in Parmesan until slightly thickened. If the mixture is too thick, add more heavy cream as needed; season with salt and pepper, to taste.
  • Stir in pasta and gently toss to combine.
  • Serve immediately with chicken, garnished with tomatoes and parsley, if desired.




Cajun-chicken, tomatoes and Parmesan Cheese topped over a bed of creamy penne pasta.


Join the Conversation
Recipe Rating

8 thoughts on “Cajun Chicken Pasta

  1. This makes me think of when O’Charley’s first opened here when I was a junior in high school and I thought it was SO good. Cajun chicken pasta was my favorite thing to order! This looks way better than that. Thanks for the recipe!

  2. Looks like you’ve updated this recipe to a new one that looks really yummy. Do you still have the old one with the cajun spice mix amounts? That meal is a favorite of ours and if I lose that recipe I’m in big trouble! Thanks for your help!

    1. Hi Lynn! Yes I deleted the old one but I still have that other version’s cajun mix seasoning. Here it is below:

      1 Tablespoon Onion Powder
      1 Tablespoon Dried Thyme
      1 Tablespoon Ground Red Pepper (Cayenne)
      2 Tablespoons Garlic Powder
      2 Tablespoons Paprika
      1 Tablespoon Salt
      1 Tablespoon Black Pepper
      Combine all together in a small air tight container. Store for up to six months.

  3. It would appear that since this makes 4 servings that a serving is 1/2 a chicken breast?? Maybe for a child but for an adult??? This recipe would be just about right for my husband and me so I guess we’ll be eating 2 servings each. 🙂 Would I be the only one who thinks half a chicken breast is not really a dinner-size meal?

    1. We get the large frozen chicken breasts at Costco, so my family only eats half of them. That’s where I get the two servings from one 🙂

  4. Everyone loved it! I didn’t have penne so I used spaghetti. I think penne would definitely have been much better.

© Life In The Lofthouse.
Site by